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Drug Evaluation & Research

CDERNEW-TEXT 11/7 - 9/2007


Friday, November 9, 2007

November 9, 2007

Approved Drug Products with Therapeutic Equivalence Evaluations Orange
Book http://www.fda.gov/cder/orange/default.htm

Drug Shortage

Drug to be Discontinued; Procanbid (Procanamide Hydrochloride
Extended-Release Tablets)
http://www.fda.gov/cder/drug/shortages/default.htm#Procanbid

New and Generic Drug Approvals
http://www.accessdata.fda.gov/scripts/cder/drugsatfda/index.cfm

Brevibloc (esmolol hydrochloride) IV, Baxter Healthcare, Labeling
Revision

LOVAZA (omega-3-acid ethyl esters) Capsules, Reliant Pharma, Labeling
Revision

PEPCID (famotidine) Oral Suspension, Salix Pharma, Labeling Revision

PEPCID (famotidine) Tablets, Merck & Co., Labeling Revision

PEPCID (famotidine) Injection , Merck & Co., Labeling Revision

PEPCID (famotidine) Injection Premixed, Merck & Co., Labeling Revision

November 8, 2007

Drug Approval Reports http://www.fda.gov/cder/rdmt/default.htm

Fast Track Fiscal Year 2007
http://www.fda.gov/cder/rdmt/INTERNETFTSTATS.HTM

Fast Track Designation (FY 1998 - FY 2006)
http://www.fda.gov/cder/rdmt/internetftstat_FY98-06.HTM


NDA and BLA Approvals http://www.fda.gov/cder/rdmt/InternetNDA07.htm

NME Drug and New Biologic Approvals
http://www.fda.gov/cder/rdmt/InternetNME07.htm

Priority NDA and BLA Approvals
http://www.fda.gov/cder/rdmt/InternetPriority07.htm

FDA strengthens the Boxed Warnings and approves other safety labeling
changes for erythropoiesis-stimulating agents (ESAs). [FDA News
http://www.fda.gov/bbs/topics/NEWS/2007/NEW01740.html ]; [Public Health
Advisory] http://www.fda.gov/cder/drug/advisory/RHE200711.htm ;
[Information for Healthcare Professionals]
http://www.fda.gov/cder/drug/InfoSheets/HCP/RHE200711HCP.htm

Guidance for Industry: Chronic Obstructive Pulmonary Disease: Developing
Drugs for Treatment [PDF http://www.fda.gov/cder/guidance/7875dft.pdf ]
or [HTML http://www.fda.gov/cder/guidance/7875dft.htm ]

New and Generic Drug Approvals
http://www.accessdata.fda.gov/scripts/cder/drugsatfda/index.cfm

CELEBREX (celecoxib) Capsules, G.D. Searle, Labeling Revision

Colazal (balsalazide disodium) Capsules, Salix Pharma, Labeling Revision


Fever All (acetaminophen) Rectal Suppositories, Actavis, Manufacturing
Change or Addition

Inderal LA Capsules, Wyeth Pharma, Labeling Revision

Lamivudine/Stavudine Tablets, Matrix Labs, Tentative Approval

Lovastatin Tablets, Lupin Ltd., Approval

Myfortic (mycophenolic acid) Delayed-Release Tablets, Novartis Pharma,
Labeling Revision

Sterile Water Injection, Hospira Inc., Package Change

Zometa (zoledronic acid) Injection, Novartis Pharma, Labeling Revision

November 7, 2007

Adolescent Over-the-Counter (OTC) Drug Product Use: A Public Workshop,
December 6 and 7, 2007
http://www.fda.gov/cder/meeting/adolescent_OTC.htm

Drug Firm Annual Registration Status
http://www.fda.gov/cder/dfars/default.htm


Drugs@FDA Downloadable Data Files
http://www.fda.gov/cder/drugsatfda/datafiles/default.htm

(updated)

National Drug Code Directory Search
http://www.fda.gov/cder/ndc/database/default.htm


National Drug Code Directory Download
http://www.fda.gov/cder/ndc/index.htm

Notice of Violation: Natrecor (nesiritide) for injection
http://www.fda.gov/cder/warn/warn2007.htm#November


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CDERNEW-TEXT 11/5 & 6/2007


Tuesday, November 6, 2007

November 6, 2007

Drug Approval Reports http://www.fda.gov/cder/rdmt/default.htm

NDA and BLA Approvals http://www.fda.gov/cder/rdmt/InternetNDA07.htm

NME Drug and New Biologic Approvals
http://www.fda.gov/cder/rdmt/InternetNME07.htm

Priority NDA and BLA Approvals
http://www.fda.gov/cder/rdmt/InternetPriority07.htm

New and Generic Drug Approvals
http://www.accessdata.fda.gov/scripts/cder/drugsatfda/index.cfm

Ampicillin Injection, Sandoz Inc., Microbiology

Ampicillin and Sulbactam Injection, Sandoz Inc., Microbiology

Ampicillin and Sulbactam Injection, Sandoz Inc., Microbiology

Ampicillin and Sulbactam Injection, Sandoz Inc., Microbiology

Baclofen 20mg Tablets, Actavis Totowa, Approval

Baclofen 10mg Tablets, Actavis Totowa, Approval

Benzonatate Capsules, KV Pharma, Approval

Ciprofloxacin Extended-release Tablets, Dr. Reddy's Labs, Approval

Lupron Depot (leuprolide acetate 3.75mg) Depot Suspension, Tap Pharma,
Labeling Revision

Lupron Depot (leuprolide acetate11.25mg) Depot Suspension, Tap Pharma,
Labeling Revision

Norvasc (amlodipine besylate) Tablets, Pfizer Inc., Labeling Revision

Prednisolone Sodium Phosphate Oral Solution, Vintage Pharma, Approval

Rivastigmine Tartrate Capsules, Dr. Reddy's Labs, Approval

SYMBICORT (budesonide/formoterol fumarate dihydrate) Inhalation Aerosol,
AstraZeneca Pharma, Labeling Revision

Vasotec (enalapril maleate)Tablets, Biovail Tech, Labeling Revision

Vaseretic (enalapril maleate/hydrochlorothiazide) Tablets, Biovail Tech,
Labeling Revision


November 5, 2007

FDA requests the marketing suspension of Trasylol (aprotinin)
http://www.fda.gov/bbs/topics/NEWS/2007/NEW01738.html

Guidance for Industry: Comprehensive List of Guidance Documents [PDF
http://www.fda.gov/cder/guidance/CompList11_2007.pdf ]

Guidance for Industry: New/Revised/Withdrawn List for 2007 [PDF
http://www.fda.gov/cder/guidance/newrevwithdrawn200710.pdf ]

New and Generic Drug Approvals
http://www.accessdata.fda.gov/scripts/cder/drugsatfda/index.cfm

Atenolol Tablets, Aurobindo Pharma, Approval

Carvedilol Tablets, Pliva Hrvatska, Approval

Dalmane (flurazepam hydrochloride) Capsules, Valeant Pharma, Labeling
Revision

Digoxin Tablets, West-ward Pharma, Approval

Doral (quazepam) Tablets, Questcor Pharma, Labeling Revision

Finasteride Tablets, Aurobindo Pharma, Approval

Kinlytic (Urokinase) Injection, ImaRx Therapeutics, Labeling Revision

PREVPAC (lansoprazole/amoxicillin/ clarithromycin), Tap Pharma, Labeling
Revision

Primacor (milrinone lactate) Injection, Sanofi-Aventis, Labeling
Revision

Primacor (milrinone lactate) in 5% Dextrose Injection, Sanofi-Aventis,
Labeling Revision

Saizen (somatropin [rDNA origin]) Injection, EMD Serono Inc., Package
Change

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posted by Mags @ 5:15 PM, ,